T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a Phase 1/2 clinical trial

SARS-CoV-2, the causative agent of COVID-19, has caused a global pandemic and safe, effective vaccines are urgently needed. Strong, Th1-skewed T cell responses can drive protective humoral and cell-mediated immune responses, and may reduce the potential for disease enhancement. Cytotoxic T cells cle...

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Bibliographic Details
Main Authors: Ewer, K, Barrett, J, Belij-Rammerstorfer, S, Lambe, T, Hill, A, Pollard, A, Gilbert, S, Et al.
Other Authors: Oxford COVID Vaccine Trial Group
Format: Journal article
Language:English
Published: Springer Nature 2020