ZIC-cHILIC as a fractionation method for sensitive and powerful shotgun proteomics.
Multidimensional liquid chromatography (LC) combined with mass spectrometry (MS) has become a standard technique in proteomics to reduce sample complexity and to tackle the dynamic range in protein abundance. Fractionation is necessary to obtain a comprehensive analysis of complex biological samples...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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