Role of Syk in B-cell development and antigen-receptor signaling.

Role of Syk in B-cell development and antigen-receptor signaling.

Antigen receptors (BCRs) on developing B lymphocytes play two opposing roles-promoting survival of cells that may later bind a foreign antigen and inhibiting survival of cells that bind too strongly to self-antigens. It is not known how these opposing outcomes are signaled by BCRs on immature B cell...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Cornall, R, Cheng, A, Pawson, T, Goodnow, C
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2000

समान संसाधन

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Regulation of B cell antigen receptor signaling by the Lyn/CD22/SHP1 pathway.
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The regulation of self-reactive B cells.
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Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen.
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प्रकाशित: (1992)

Monovalent and Multivalent Ligation of the B Cell Receptor Exhibit Differential Dependence upon Syk and Src Family Kinases
द्वारा: Mukherjee, Sayak, और अन्य
प्रकाशित: (2014)

Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival (vol 35, pg 3655, 2005)
द्वारा: Ferry, H, और अन्य
प्रकाशित: (2005)

Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival.
द्वारा: Ferry, H, और अन्य
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B cell antigen receptor signaling and internalization are mutually exclusive events.
द्वारा: Ping Hou, और अन्य
प्रकाशित: (2006-07-01)

Mercury alters endogenous phosphorylation profiles of SYK in murine B cells
द्वारा: Joseph A. Caruso, और अन्य
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SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia
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Role of Specific B-Cell Receptor Antigens in Lymphomagenesis
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P1267: HSP110 FAVORS BCR SIGNALING THROUGH SYK PHOSPHORYLATION IN DIFFUSE LARGE B CELL LYMPHOMA
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प्रकाशित: (2017-10-01)

Involvement of B Cells, Immunoglobulins, and Syk in the Pathogenesis of Abdominal Aortic Aneurysm
द्वारा: Aya Furusho, और अन्य
प्रकाशित: (2018-03-01)

Seeking to Develop Global SYK-Ness
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The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling
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प्रकाशित: (2018-07-01)

Erratum: Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22- independent pathways affecting BCR regulation and B cell survival (European Journal of Immunology (2005) vol. 35 (12) (3714) 10.1002/eji.200535247)
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प्रकाशित: (2005)

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Correction: Syk Signaling in Dendritic Cells Orchestrates Innate Resistance to Systemic Fungal Infection.
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Source data for: Hodgson et al, NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance, Communications Biology 2022
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Signaling Response to Transient Redox Stress in Human Isolated T Cells: Molecular Sensor Role of Syk Kinase and Functional Involvement of IL2 Receptor and L-Selectine
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Vector models and generalized SYK models
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प्रकाशित: (2017-05-01)