Role of Syk in B-cell development and antigen-receptor signaling.

Role of Syk in B-cell development and antigen-receptor signaling.

Antigen receptors (BCRs) on developing B lymphocytes play two opposing roles-promoting survival of cells that may later bind a foreign antigen and inhibiting survival of cells that bind too strongly to self-antigens. It is not known how these opposing outcomes are signaled by BCRs on immature B cell...

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Dettagli Bibliografici
Autori principali:	Cornall, R, Cheng, A, Pawson, T, Goodnow, C
Natura:	Journal article
Lingua:	English
Pubblicazione:	2000

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