Control of experimental inflammatory bowel disease by regulatory T cells.

A helper T cell type 1-mediated colitis driven by enteric bacteria develops in severe combined immunodeficient mice after transfer of CD45RB(high)CD4(+) T cells. Development of disease can be prevented by cotransfer of the reciprocal CD45RB(low) subset. Analysis of the mechanism of immune suppressio...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Asseman, C, Fowler, S, Powrie, F
Format: Journal article
Język:English
Wydane: 2000