Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene.

Interferon consensus sequence binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Mice with a null mutation of ICSBP exhibit two prominent phenotypes related to previously described activities of the IRF family. The first is enhanced susceptibili...

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Bibliographic Details
Main Authors: Holtschke, T, Löhler, J, Kanno, Y, Fehr, T, Giese, N, Rosenbauer, F, Lou, J, Knobeloch, K, Gabriele, L, Waring, J, Bachmann, M, Zinkernagel, R, Morse, H, Ozato, K, Horak, I
Format: Journal article
Language:English
Published: 1996