Non-glycosidic compounds can stimulate both human and mouse iNKT cells.

Invariant natural killer T (iNKT) cells recognize CD1d/glycolipid complexes and upon activation with synthetic agonists display immunostimulatory properties. We have previously described that the non-glycosidic CD1d-binding lipid, threitolceramide (ThrCer) activates murine and human iNKT cells. Here...

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Bibliographic Details
Main Authors: Jukes, J, Gileadi, U, Ghadbane, H, Yu, T, Shepherd, D, Cox, L, Besra, G, Cerundolo, V
Format: Journal article
Language:English
Published: Wiley 2016