A SARS-CoV-2 recombinant spike protein vaccine (S-268019-b) for COVID-19 prevention during the Omicron-dominant period: a phase 3, randomised, placebo-controlled clinical trial

Clinical trials of new vaccines based on existing variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) are often impacted by the emergence of new virus variants. We evaluated the efficacy, immunogenicity, and safety of S-268019-b, a recombinant spike protein subunit vaccine based...

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Bibliographic Details
Main Authors: Thiem, VD, Anh, PTV, Men, CV, Hung, DT, Pollard, AJ, Kamitani, A, Tada, Y, Fukuyama, H, Iwasaki, Y, Ariyasu, M, Sonoyama, T
Format: Journal article
Language:English
Published: Elsevier 2024