The assessment of antigen-specific CD8+ T cells through the combination of MHC class I tetramer and intracellular staining.

Peptide-bound histocompatibility leukocyte antigen (HLA) class I tetramers enable a precise identification of antigen-specific CD8+ T cells using flow cytometry. The combination of this technology with intracellular staining techniques opens up significantly better ways of studying these cells than...

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Bibliographic Details
Main Authors: Appay, V, Rowland-Jones, S
Format: Journal article
Language:English
Published: 2002