What have human experimental overfeeding studies taught us about adipose tissue expansion and susceptibility to obesity and metabolic complications?

Overfeeding experiments, in which we impose short-term positive energy balance, help unravel the cellular, physiological and behavioural adaptations to nutrient excess. These studies mimic longer-term mismatched energy expenditure and intake. There is considerable inter-individual heterogeneity in t...

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Bibliographic Details
Main Authors: Cuthbertson, D, Steele, T, Wilding, J, Halford, J, Harrold, J, Hamer, M, Karpe, F
Format: Journal article
Language:English
Published: Nature Publishing Group 2017