Role for the obesity-related FTO gene in the cellular sensing of amino acids.

Role for the obesity-related FTO gene in the cellular sensing of amino acids.

SNPs in the first intron of FTO (fat mass and obesity associated) are strongly associated with human obesity. While it is not yet formally established that this effect is mediated through the actions of the FTO protein itself, loss of function mutations in FTO or its murine homologue Fto result in s...

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Détails bibliographiques
Auteurs principaux: Gulati, P, Cheung, M, Antrobus, R, Church, C, Harding, H, Tung, Y, Rimmington, D, Ma, M, Ron, D, Lehner, P, Ashcroft, F, Cox, R, Coll, A, O'Rahilly, S, Yeo, G
Format: Journal article
Langue:English
Publié: 2013

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