High intraluminal pressure via increased release of hydrogen peroxide maintains arteriolar responsiveness to angiotensin II

Geahča maid

• High intraluminal pressure reduces AT1 receptor internalization and maintains arteriolar constrictions to angiotensin II
  Dahkki: Koller, A, et al.
  Almmustuhtton: (2007)
• High intraluminal pressure via H2O2 upregulates arteriolar constrictions to angiotensin II by increasing the functional availability of AT1 receptors.
  Dahkki: Bagi, Z, et al.
  Almmustuhtton: (2008)
• High intraluminal pressure reduces tachyphylaxis to angiotensin II in isolated arterioles
  Dahkki: Koller, A, et al.
  Almmustuhtton: (2006)
• Hydrogen peroxide modulates arteriolar myogenic tone by activating multiple vasomotor mechanisms
  Dahkki: Cseko, C, et al.
  Almmustuhtton: (2004)
• Type 2 diabetic mice have increased arteriolar tone and blood pressure: enhanced release of COX-2-derived constrictor prostaglandins.
  Dahkki: Bagi, Z, et al.
  Almmustuhtton: (2005)