Probing the structural basis of RecQ helicase function.

RecQ helicases are a ubiquitous family of DNA unwinding enzymes required to preserve genome integrity, thus preventing premature aging and cancer formation. The five human representatives of this family play non-redundant roles in the suppression of genome instability using a combination of enzymati...

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Bibliographic Details
Main Authors: Vindigni, A, Marino, F, Gileadi, O
Format: Journal article
Language:English
Published: 2010