Machine learning model for sequence-driven DNA G-quadruplex formation

We describe a sequence-based computational model to predict DNA G-quadruplex (G4) formation. The model was developed using large-scale machine learning from an extensive experimental G4-formation dataset, recently obtained for the human genome via G4-seq methodology. Our model differentiates many wi...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Sahakyan, A, Chambers, V, Marsico, G, Santner, T, Di Antonio, M, Balasubramanian, S
פורמט: Journal article
שפה:English
יצא לאור: Springer Nature 2017