Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication

Human immunodeficiency virus 1 (HIV-1) is a life-threatening pathogen that still lacks a curative therapy or vaccine. Despite the reduction in AIDS-related deaths achieved by current antiretroviral therapies, drawbacks including drug resistance and the failure to eradicate infection highlight the ne...

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Bibliographic Details
Main Authors: Borrmann, H, Davies, R, Dickinson, M, Pedroza-Pacheco, I, Schilling, M, Vaughan-Jackson, A, Magri, A, James, W, Balfe, P, Borrow, P, Jane McKeating, JA, Zhuang, X
Format: Journal article
Language:English
Published: Springer Nature 2020