Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage.

OBJECTIVE: Articular chondrocytes are surrounded by an extracellular pool of fibroblast growth factor 2 (FGF-2). We undertook this study to investigate the possible role of FGF-2 in aggrecan catabolism by aggrecanase in human articular cartilage. METHODS: Aggrecan catabolism was induced by interleu...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Sawaji, Y, Hynes, J, Vincent, T, Saklatvala, J
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2008