Gene x gene interactions in genome wide association studies

Gene x gene interactions in genome wide association studies

<p>Genome wide association studies (GWAS) have revolutionized our approach to mapping genetic determinants of complex human diseases. However, even with success from recent studies, we have typically been able to explain only a fraction of the trait heritability. GWAS are typically analysed by...

书目详细资料
主要作者:	Bhattacharya, K
其他作者:	Morris, A
格式:	Thesis
语言:	English
出版:	2014
主题:	Statistics (see also social sciences) Bioinformatics (technology) Bioinformatics (life sciences) Mathematical genetics and bioinformatics (statistics) Mathematical biology Genetics (life sciences) Mathematics

相似书籍

Extensions of the case-control design in genome-wide association studies
由: Loizides, C
出版: (2012)

Using phylogeny to improve genome-wide distant homology recognition
由: Abeln, S, et al.
出版: (2007)

Quantifying the underestimation of relative risks from genome-wide association studies
由: Spencer, C, et al.
出版: (2011)

Protein protein interactions, evolutionary rate, abundance and age
由: Saeed, R, et al.
出版: (2006)

Cotranslational protein folding - fact or fiction?
由: Deane, C, et al.
出版: (2007)

Modelling sequential protein folding under kinetic control
由: Huard, F, et al.
出版: (2006)

A statistical approach using network structure in the prediction of protein characteristics
由: Chen, P, et al.
出版: (2007)

Multilocus approaches to the detection of disease susceptibility regions: methods and applications
由: Ciampa, J
出版: (2012)

Statistical HLA type imputation from large and heterogeneous datasets
由: Dilthey, A
出版: (2012)

Rahnuma: hypergraph-based tool for metabolic pathway prediction and network comparison
由: Mithani, A, et al.
出版: (2009)

Increasing statistical power and generalizability in genomics microarray research
由: Ramasamy, A
出版: (2009)

HLA*IMP - an integrated framework for imputing classical HLA alleles from SNP genotypes
由: Dilthey, A, et al.
出版: (2011)

Bayesian methods for multivariate phenotype analysis in genome-wide association studies
由: Iotchkova, V
出版: (2013)

Design and analysis of genome-wide association studies
由: Barrett, J
出版: (2008)

An integrated genomic approach for the identification and analysis of single nucleotide polymorphisms that affect cancer in humans
由: Repapi, E
出版: (2013)

Bayesian methods for estimating human ancestry using whole genome SNP data
由: Churchhouse, C
出版: (2012)

The estimation of recombination rates from population genetic data
由: Auton, A
出版: (2007)

Statistical challenges in the detection of mutation and variation using high throughput sequencing
由: Pfeifer, S
出版: (2012)

Statistical and Computational Methodology for the Analysis of Forensic DNA Mixtures with Artefacts
由: Graversen, T
出版: (2014)

Exploring the fold space preferences of ancient and newborn protein superfamilies
由: Edwards, H, et al.
出版: (2014)

Application of the Neutral Indel Model to genome sequences for diverse metazoans
由: Meader, S
出版: (2010)

Protein loop structure prediction
由: Choi, Y
出版: (2011)

Large-scale genetic analysis of quantitative traits
由: Randall, J, et al.
出版: (2012)

A method for the identification of biological pathways
由: Honti, F
出版: (2014)

On genetic variants underlying common disease
由: Hechter, E
出版: (2011)

Bayesian and frequentist methods and analyses of genome-wide association studies
由: Vukcevic, D
出版: (2009)

Selection along the HIV-1 genome through the CTL mediated immune response
由: Palmer, D
出版: (2014)

Imputation aided analysis of the association between autoimmune diseases and the MHC
由: Moutsianas, L
出版: (2011)

Inferring the fine-scale structure and evolution of recombination from high-throughput genome sequencing
由: Venn, O
出版: (2013)

The evolutionary dynamics of neutral networks: lessons from RNA
由: Rendel, M
出版: (2008)

Genome-wide DNaseI hypersensitive sites profiles in laboratory mouse strains by DNase-seq
由: Hosseini, M
出版: (2013)

Protein fold evolution on completed genomes: distinguishing between young and old folds
由: Abeln, S, et al.
出版: (2007)

Genome annotation and selectional analysis of viral evolution
由: de Groot, S
出版: (2008)

Fold recognition and alignment in the ‘twilight zone’
由: Hill, J, et al.
出版: (2013)

Statistical methods for the analysis of genetic association studies
由: Su, Z
出版: (2008)

Bayesian methods for fine mapping in genetic association studies
由: Frangou, E
出版: (2013)

Genes contributing to variation in fear-related behaviour
由: Krohn, J, et al.
出版: (2013)

A robust clustering algorithm for identifying problematic samples in genome-wide association studies
由: Bellenguez, C, et al.
出版: (2012)

Statistical models for single-cell data
由: Pierson, E
出版: (2015)

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
由: Howie, B, et al.
出版: (2009)