RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro

Fat distribution is an independent cardiometabolic risk factor. However, its molecular and cellular underpinnings remain obscure. Here we demonstrate that two independent GWAS signals at RSPO3, which are associated with increased body mass index-adjusted waist-to-hip ratio, act to specifically incre...

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Dettagli Bibliografici
Autori principali: Loh, NY, Minchin, JE, Pinnick, KE, Verma, M, Denton, N, Neville, M, McCarthy, M, Mahajan, A, Karpe, F, Christodoulides, C
Natura: Journal article
Lingua:English
Pubblicazione: Springer Nature 2020