Exploiting the carboxylate chemical shift to resolve degenerate resonances in spectra of 13C-labelled glycosaminoglycans.

Glycosaminoglycans (GAG) are important vertebrate extracellular matrix polysaccharides that comprise repeated units of an acidic and an N-acetylated sugar. The constituent acidic sugars are central to their biological functions, but have been largely inaccessible to NMR because the (1)H resonances o...

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Bibliographic Details
Main Authors: Colebrooke, SA, Blundell, C, DeAngelis, P, Campbell, I, Almond, A
Format: Journal article
Language:English
Published: 2005