Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome.

GATA-1 is the founding member of a transcription factor family that regulates growth and maturation of a diverse set of tissues. GATA-1 is expressed primarily in hematopoietic cells and is essential for proper development of erythroid cells, megakaryocytes, eosinophils, and mast cells. Although loss...

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Bibliographic Details
Main Authors: Gurbuxani, S, Vyas, P, Crispino, J
Format: Journal article
Language:English
Published: 2004