Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome.
GATA-1 is the founding member of a transcription factor family that regulates growth and maturation of a diverse set of tissues. GATA-1 is expressed primarily in hematopoietic cells and is essential for proper development of erythroid cells, megakaryocytes, eosinophils, and mast cells. Although loss...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2004
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