switchde: inference of switch-like differential expression along single-cell trajectories

MOTIVATION: Pseudotime analyses of single-cell RNA-seq data have become increasingly common. Typically, a latent trajectory corresponding to a biological process of interest - such as differentiation or cell cycle - is discovered. However, relatively little attention has been paid to modelling the d...

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Bibliographic Details
Main Authors: Campbell, K, Yau, C
Format: Journal article
Language:English
Published: Oxford University Press 2016