Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T-cells
Planar supported lipid bilayers (PSLBs) presenting T cell receptor (TCR) ligands and ICAM-1 induce budding of extracellular microvesicles enriched in functional TCR, defined here as synaptic ectosomes (SE), from helper T cells. SE bind peptide-MHC directly exporting TCR into the synaptic cleft, but...
Egile Nagusiak: | , , , , , , , , , , , , , , , |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
eLife Sciences Publications
2019
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