Genetic pathways in colorectal cancer.

Genetic pathways in colorectal cancer.

The model of colorectal tumorigenesis put forward by Fearon and Vogelstein has had great influence on molecular oncology. They proposed that a series of mutations occur in the progression from normal cells to colorectal cancer and that these mutations are associated with the histological features of...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Ilyas, M, Tomlinson, I
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	1996

Eitemau Tebyg

Genetic pathways in colorectal and other cancers.
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Cyhoeddwyd: (1999)

Genetic pathways in colorectal and other cancers.
gan: Ilyas, M, et al.
Cyhoeddwyd: (1999)

Colorectal cancer and genetic alterations in the Wnt pathway.
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A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer.
gan: Tomlinson, I, et al.
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Genetic prognostic markers in colorectal cancer.
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An update on the genetics of colorectal cancer.
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Colorectal cancer genetics: from candidate genes to GWAS and back again.
gan: Tomlinson, I
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Molecular genetics of colon cancer.
gan: Tomlinson, I, et al.
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Different pathways of colorectal carcinogenesis and their clinical pictures.
gan: Tomlinson, I
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Genetic prognostic and predictive markers in colorectal cancer.
gan: Walther, A, et al.
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Bcl-2 expression in colorectal tumors: evidence of different pathways in sporadic and ulcerative-colitis-associated carcinomas.
gan: Ilyas, M, et al.
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Allele loss, replication errors and loss of expression of E-cadherin in colorectal cancers.
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The Mendelian colorectal cancer syndromes
gan: Tomlinson, I
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Allele loss occurs frequently at hMLH1, but rarely at hMSH2, in sporadic colorectal cancers with microsatellite instability.
gan: Tomlinson, I, et al.
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Beta-catenin mutations in cell lines established from human colorectal cancers.
gan: Ilyas, M, et al.
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Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes.
gan: Wang, Z, et al.
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Mutations within Wnt pathway genes in sporadic colorectal cancers and cell lines.
gan: Suraweera, N, et al.
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The low frequency of beta-catenin mutations in cell lines established from human colorectal cancers
gan: Ilyas, M, et al.
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Loss of Bcl-2 expression correlates with tumour recurrence in colorectal cancer.
gan: Ilyas, M, et al.
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Genetic Variants in the Mitochondrial Thymidylate Biosynthesis Pathway Increase Colorectal Cancer Risk
gan: Entesar M. Arrait, et al.
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Clinico-pathological features and p53 expression in left-sided sporadic colorectal cancers with and without microsatellite instability.
gan: Ilyas, M, et al.
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COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.
gan: Tomlinson, I, et al.
Cyhoeddwyd: (2010)

Erratum: Genetic prognostic and predictive markers in colorectal cancer (Nature Reviews Cancer (2009) 9 (489-499))
gan: Walther, A, et al.
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Reciprocity between membranous and nuclear expression of beta-catenin in colorectal tumours.
gan: Hao, X, et al.
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Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.
gan: Carvajal-Carmona, L, et al.
Cyhoeddwyd: (2013)

Chromosomal instability, colorectal cancer and taxane resistance.
gan: Swanton, C, et al.
Cyhoeddwyd: (2006)

Refining molecular analysis in the pathways of colorectal carcinogenesis.
gan: Rowan, A, et al.
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Tumour recurrence is associated with Jass grouping but not with differences in E-cadherin expression in moderately differentiated Dukes' B colorectal cancers.
gan: Ilyas, M, et al.
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Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer.
gan: Whiffin, N, et al.
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Sex hormones and genetic variants in hormone metabolic pathways associated with the risk of colorectal cancer
gan: Shuwei Li, et al.
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Effects of genetic variations in the Adiponectin pathway genes on the risk of colorectal cancer in the Chinese population
gan: He Bangshun, et al.
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Hereditary colorectal cancer: genetics and screening diagnostics
gan: O. I. Kit, et al.
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Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma.
gan: Hao, X, et al.
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Optimising methods for determining RER status in colorectal cancers.
gan: Stone, J, et al.
Cyhoeddwyd: (2000)

Evidence against a major genetic basis for combined breast and colorectal cancer susceptibility.
gan: Brinkman, H, et al.
Cyhoeddwyd: (2006)

Defining the clinical phenotype of hereditary nonpolyposis colorectal cancer
gan: Beck, N, et al.
Cyhoeddwyd: (1999)

Expression of hippo pathway in colorectal cancer
gan: Kun Liang, et al.
Cyhoeddwyd: (2014-01-01)

Apparent Mendelian inheritance of breast and colorectal cancer: chance, genetic heterogeneity or a new gene?
gan: Lipton, L, et al.
Cyhoeddwyd: (2001)

Towards a multiscale model of colorectal cancer.
gan: van Leeuwen, I, et al.
Cyhoeddwyd: (2007)

Genetic testing is important in families with a history suggestive of hereditary non-polyposis colorectal cancer even if the Amsterdam criteria are not fulfilled.
gan: Beck, N, et al.
Cyhoeddwyd: (1997)