The 3-phosphoinositide–dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

Cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) signalling is essential for the proliferation of Plasmodium falciparum malaria blood stage parasites. The mechanisms regulating the activity of the catalytic subunit PfPKAc, however, are only partially understood, and PfPKAc func...

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Bibliographic Details
Main Authors: Hitz, E, Wiedemar, N, Passecker, A, Graça, BAS, Scheurer, C, Wittlin, S, Brancucci, NMB, Vakonakis, I, Mäser, P, Voss, TS
Format: Journal article
Language:English
Published: Public Library of Science 2021