Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis
<p><strong>Objectives</strong> Nerve growth factor (NGF) has emerged as a key driver of pain in osteoarthritis (OA) and antibodies to NGF are potent analgesics in human disease. Here, we validate a novel vaccine strategy to generate anti-NGF antibodies for reversal of pain behaviou...
| Main Authors: | , , , , , , , , |
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
BMJ Publishing Group
2019
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