Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis

<p><strong>Objectives</strong> Nerve growth factor (NGF) has emerged as a key driver of pain in osteoarthritis (OA) and antibodies to NGF are potent analgesics in human disease. Here, we validate a novel vaccine strategy to generate anti-NGF antibodies for reversal of pain behaviou...

Popoln opis

Bibliografske podrobnosti
Main Authors: Von Loga, I, El-Turabi, A, Jostins, L, Miotla-Zarebska, J, Mackay-Alderson, J, Zeltins, A, Parisi, I, Bachmann, M, Vincent, T
Format: Journal article
Jezik:English
Izdano: BMJ Publishing Group 2019