Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis
<p><strong>Objectives</strong> Nerve growth factor (NGF) has emerged as a key driver of pain in osteoarthritis (OA) and antibodies to NGF are potent analgesics in human disease. Here, we validate a novel vaccine strategy to generate anti-NGF antibodies for reversal of pain behaviou...
Main Authors: | , , , , , , , , |
---|---|
Format: | Journal article |
Jezik: | English |
Izdano: |
BMJ Publishing Group
2019
|