An autonomous oscillation times and executes centriole biogenesis
The accurate timing and execution of organelle biogenesis is crucial for cell physiology. Centriole biogenesis is regulated by Polo-like kinase 4 (Plk4) and initiates in S-phase when a daughter centriole grows from the side of a pre-existing mother. Here, we show that a Plk4 oscillation at the base...
Main Authors: | , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2020
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