SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages

Phagocytosis is a pivotal process by which macrophages eliminate microorganisms after recognition by pathogen sensors. Here we unexpectedly found that the self ligand and cell surface receptor SLAM functioned not only as a costimulatory molecule but also as a microbial sensor that controlled the kil...

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Bibliographic Details
Main Authors: Berger, S, Romero, X, Ma, C, Wang, G, Faubion, W, Liao, G, Compeer, E, Keszei, M, Rameh, L, Wang, N, Boes, M, Regueiro, J, Reinecker, H, Terhorst, C
Format: Journal article
Language:English
Published: Springer Nature 2010