Dissociation of the human spliceosomal U1 snRNP complex
The non-covalent interactions which maintain protein-RNA complexes such as U1 snRNP in human spliceosome were investigated using nanoflow ESI-MS technique. The reconstituted U1 snRNP complex comprised core domain of Sm proteins and snRNA. The instrument pressure was varied by partial closure of rota...
| Main Authors: | , , , |
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| Format: | Conference item |
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2002
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