Dissociation of the human spliceosomal U1 snRNP complex
The non-covalent interactions which maintain protein-RNA complexes such as U1 snRNP in human spliceosome were investigated using nanoflow ESI-MS technique. The reconstituted U1 snRNP complex comprised core domain of Sm proteins and snRNA. The instrument pressure was varied by partial closure of rota...
Main Authors: | Hernández, H, Krummel, D, Nagai, K, Robinson, C |
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Formato: | Conference item |
Publicado: |
2002
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