Dissociation of the human spliceosomal U1 snRNP complex

The non-covalent interactions which maintain protein-RNA complexes such as U1 snRNP in human spliceosome were investigated using nanoflow ESI-MS technique. The reconstituted U1 snRNP complex comprised core domain of Sm proteins and snRNA. The instrument pressure was varied by partial closure of rota...

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Detalles Bibliográficos
Main Authors: Hernández, H, Krummel, D, Nagai, K, Robinson, C
Formato: Conference item
Publicado: 2002

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