Dissociation of the human spliceosomal U1 snRNP complex
The non-covalent interactions which maintain protein-RNA complexes such as U1 snRNP in human spliceosome were investigated using nanoflow ESI-MS technique. The reconstituted U1 snRNP complex comprised core domain of Sm proteins and snRNA. The instrument pressure was varied by partial closure of rota...
| Autori principali: | , , , |
|---|---|
| Natura: | Conference item |
| Pubblicazione: |
2002
|