Perturbation of PALB2 function by the T413S mutation found in small cell lung cancer
<p>Background: Germline mutations in the PALB2 gene are associated with the genetic disorder Fanconi anaemia and increased predisposition to cancer. Disease-associated variants are mainly protein-truncating mutations, whereas a few missense substitutions are reported to perturb its interaction...
| Main Authors: | , , |
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| Format: | Journal article |
| Published: |
F1000Research
2017
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