Selective binding of AIRAPL tandem UIMs to lys48-linked tri-ubiquitin chains

Selective binding of AIRAPL tandem UIMs to lys48-linked tri-ubiquitin chains

<p>Lys48-linked ubiquitin chains act as the main targeting signals for protein degradation by the proteasome. Here we report selective binding of AIRAPL, a protein that associates with the proteasome upon exposure to arsenite, to Lys48-linked tri-ubiquitin chains. AIRAPL comprises two ubiquiti...

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Detalles Bibliográficos
Main Authors: Rahighi, S, Braunstein, I, Ternette, N, Kessler, B, Kawasaki, M, Kato, R, Matsui, T, Weiss, T, Stanhill, A, Wakatsuki, S
Formato: Journal article
Publicado: Cell Press 2016

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