No evidence that extended tracts of homozygosity are associated with Alzheimer's disease

We sought to investigate the contribution of extended runs of homozygosity in a genome-wide association dataset of 1,955 Alzheimer's disease cases and 955 elderly screened controls genotyped for 529,205 autosomal single nucleotide polymorphisms. Tracts of homozygosity may mark regions inherited...

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Bibliographic Details
Main Authors: Sims, R, Dwyer, S, Harold, D, Gerrish, A, Hollingworth, P, Chapman, J, Jones, N, Abraham, R, Ivanov, D, Pahwa, J, Moskvina, V, Dowzell, K, Thomas, C, Stretton, A, Lovestone, S, Powell, J, Proitsi, P, Lupton, M, Brayne, C, Rubinsztein, D, Gill, M, Lawlor, B, Lynch, A, Morgan, K, Brown, K
Format: Journal article
Language:English
Published: 2011