Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission.

Transmission of HIV-1 via intercellular connections has been estimated as 100-1000 times more efficient than a cell-free process, perhaps in part explaining persistent viral spread in the presence of neutralizing antibodies. Such effective intercellular transfer of HIV-1 could occur through virologi...

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Bibliographic Details
Main Authors: Sowinski, S, Jolly, C, Berninghausen, O, Purbhoo, M, Chauveau, A, Köhler, K, Oddos, S, Eissmann, P, Brodsky, F, Hopkins, C, Onfelt, B, Sattentau, Q, Davis, D
Format: Journal article
Language:English
Published: 2008