Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission.
Transmission of HIV-1 via intercellular connections has been estimated as 100-1000 times more efficient than a cell-free process, perhaps in part explaining persistent viral spread in the presence of neutralizing antibodies. Such effective intercellular transfer of HIV-1 could occur through virologi...
Main Authors: | Sowinski, S, Jolly, C, Berninghausen, O, Purbhoo, M, Chauveau, A, Köhler, K, Oddos, S, Eissmann, P, Brodsky, F, Hopkins, C, Onfelt, B, Sattentau, Q, Davis, D |
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Format: | Journal article |
Language: | English |
Published: |
2008
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