Solution-based single-molecule FRET studies of K(+) channel gating in a lipid bilayer

Ion channels are dynamic multimeric proteins that often undergo multiple unsynchronized structural movements as they switch between their open and closed states. Such structural changes are difficult to measure within the context of a native lipid bilayer and have often been monitored via macroscopi...

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Bibliographic Details
Main Authors: Sadler, E, Kapanidis, A, Tucker, S
Format: Journal article
Language:English
Published: Cell Press 2016