Solution-based single-molecule FRET studies of K(+) channel gating in a lipid bilayer

Ion channels are dynamic multimeric proteins that often undergo multiple unsynchronized structural movements as they switch between their open and closed states. Such structural changes are difficult to measure within the context of a native lipid bilayer and have often been monitored via macroscopi...

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Những tác giả chính: Sadler, E, Kapanidis, A, Tucker, S
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Cell Press 2016