Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion

F-actin dynamics are known to control insulin secretion, but the point of intersection with the stimulus-secretion cascade is unknown. Here, using multiphoton imaging of β cells isolated from Lifeact-GFP transgenic mice, we show that glucose stimulation does not cause global changes in subcortical F...

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Bibliographic Details
Main Authors: Ma, W, Chang, J, Tong, J, Ho, U, Yau, B, Kebede, MA, Thorn, P
Format: Journal article
Language:English
Published: Company of Biologists 2020