The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep

Clinically effective gene therapy for Cystic Fibrosis has been a goal for over 20 years. A plasmid vector (pGM169) that generates persistent expression and reduced host inflammatory responses in mice has raised prospects for translation to the clinic. The UK CF Gene Therapy Consortium is currently e...

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Bibliographic Details
Main Authors:	Alton, E, Baker, A, Baker, E, Boyd, A, Cheng, S, Coles, R, Collie, D, Davidson, H, Davies, J, Gill, DR, Gordon, C, Griesenbach, U, Higgins, T, Hyde, S, Innes, J, McCormick, D, McGovern, M, McLachlan, G, Porteous, D, Pringle, I, Scheule, R, Shaw, D, Smith, S, Sumner-Jones, S, Tennant, P
Format:	Journal article
Language:	English
Published:	2013

The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep

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