Polymorphisms in Pvkelch12 and gene amplification of Pvplasmepsin4 in plasmodium vivax from Thailand, Lao PDR and Cambodia

Background Mutations in Pfkelch13 and Pfplasmepsin2/3 gene amplification are well-established markers for artemisinin and piperaquine resistance in Plasmodium falciparum, a widespread problem in the Greater Mekong Subregion (GMS). The Plasmodium vivax parasite population has experienced varying drug...

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Main Authors: Duanguppama, J, Mathema, V, Tripura, R, Day, N, Nguon, C, Maxay, M, Von Seidlein, L, Dhorda, M, Peto, T, Nosten, F, White, N, Dondorp, A, Imwong, M
Format: Journal article
Published: BioMed Central 2019