Targeting the nucleus: an overview of Auger-electron radionuclide therapy.

The review presented here lays out the present state of the art in the field of radionuclide therapies specifically targeted against the nucleus of cancer cells, focussing on the use of Auger-electron-emitters. Nuclear localisation of radionuclides increases DNA damage and cell kill, and, in the cas...

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Bibliographic Details
Main Authors: Cornelissen, B, Vallis, K
Format: Journal article
Language:English
Published: 2010