Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4

Fatty acid binding protein 4 (FABP4) is a fatty acid chaperone, which is induced during adipocyte differentiation. Previously we have shown that FABP4 in endothelial cells is induced by the NOTCH1 signalling pathway, the latter of which is involved in mechanisms of resistance to antiangiogenic tumou...

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Bibliographic Details
Main Authors: Harjes, U, Bridges, E, Gharpure, K, Roxanis, I, Sheldon, H, Miranda, F, Mangala, L, Pradeep, S, Lopez-Berestein, G, Ahmed, A, Fielding, B, Sood, A, Harris, A
Format: Journal article
Language:English
Published: Springer Nature 2016