Nicotinic acid receptor agonists impair myocardial contractility by energy starvation

Nicotinic acid receptor agonists have previously been shown to cause acute reductions in cardiac contractility. We sought to uncover the changes in cardiac metabolism underlying these alterations in function. In nine humans, we recorded cardiac energetics and function before and after a single oral...

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Bibliographic Details
Main Authors: Watson, WD, Timm, KN, Lewis, AJ, Miller, JJJ, Emmanuel, Y, Clarke, K, Neubauer, S, Tyler, DJ, Rider, OJ
Format: Journal article
Language:English
Published: Federation of American Society of Experimental Biology 2020