An immune basis for malaria protection by the sickle cell trait.

BACKGROUND: Malaria resistance by the sickle cell trait (genotype HbAS) has served as the prime example of genetic selection for over half a century. Nevertheless, the mechanism of this resistance remains the subject of considerable debate. While it probably involves innate factors such as the redu...

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Bibliographic Details
Main Authors: Williams, T, Mwangi, T, Roberts, D, Alexander, N, Weatherall, D, Wambua, S, Kortok, M, Snow, R, Marsh, K
Format: Journal article
Language:English
Published: 2005