Bromo-deaza-SAH: A potent and selective DOT1L inhibitor
Chemical inhibition of proteins involved in chromatin-mediated signaling is an emerging strategy to control chromatin compaction with the aim to reprogram expression networks to alter disease states. Protein methyltransferases constitute one of the protein families that participate in epigenetic con...
Main Authors: | , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2013
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