Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response

The emergence and spread of artemisinin-resistant Plasmodium falciparum, first in the Greater Mekong Subregion (GMS), and now in East Africa, is a major threat to global malaria elimination ambitions. To investigate the artemisinin resistance mechanism, transcriptome analysis was conducted of 577 P....

Full description

Bibliographic Details
Main Authors: Zhu, L, van der Pluijm, RW, Kucharski, M, Nayak, S, Tripathi, J, White, NJ, Day, NPJ, Faiz, A, Phyo, AP, Amaratunga, C, Lek, D, Ashley, EA, Nosten, F, Smithuis, F, Ginsburg, H, von Seidlein, L, Lin, K, Imwong, M, Chotivanich, K, Mayxay, M, Dhorda, M, Nguyen, HC, Nguyen, TNT, Miotto, O, Newton, PN, Jittamala, P, Tripura, R, Pukrittayakamee, S, Peto, TJ, Hien, TT, Dondorp, AM, Bozdech, Z
Format: Journal article
Language:English
Published: Springer Nature 2022