Asymmetric activation of the calcium-sensing receptor homodimer

<p>The calcium-sensing receptor (CaSR), a cell-surface sensor for Ca<sup>2+</sup>, is the master regulator of calcium homeostasis in humans and is the target of calcimimetic drugs for the treatment of parathyroid disorders<sup>1</sup>. CaSR is a family C G-protein-coupl...

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Bibliographic Details
Main Authors: Gao, Y, Robertson, MJ, Rahman, SN, Seven, AB, Zhang, C, Meyerowitz, JG, Panova, O, Hannan, FM, Thakker, RV, Bräuner-Osborne, H, Mathiesen, JM, Skiniotis, G
Format: Journal article
Language:English
Published: Springer Nature 2021