An evaluation of the efficacy of topical application of salicylic acid for the treatment of familial cylindromatosis.

BACKGROUND: Familial cylindromatosis is a rare genetic disorder, giving rise to neoplasms of the skin appendages. We have recently shown that loss of the cylindromatosis tumour suppressor gene leads to activation of NF-kappaB, a transcription factor having antiapoptotic activity. This provides a pos...

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Bibliographic Details
Main Authors: Oosterkamp, H, Neering, H, Nijman, S, Dirac, A, Mooi, W, Bernards, R, Brummelkamp, T
Format: Journal article
Language:English
Published: 2006