High-precision correlative fluorescence and electron cryo microscopy using two independent alignment markers.

Correlative light and electron microscopy (CLEM) is an emerging technique which combines functional information provided by fluorescence microscopy (FM) with the high-resolution structural information of electron microscopy (EM). So far, correlative cryo microscopy of frozen-hydrated samples has not...

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Bibliographic Details
Main Authors: Schellenberger, P, Kaufmann, R, Siebert, C, Hagen, C, Wodrich, H, Grünewald, K
Format: Journal article
Language:English
Published: Elsevier 2014